Gary Cooper
Henry Louis 'Lou' Gehrig
Teresa Wright
Eleanor Twitchell
Babe Ruth
Babe Ruth
Walter Brennan
Sam Blake
Dan Duryea
Hank Hanneman
Elsa Janssen
Christina 'Mom' Gehrig
Ludwig Stössel
Henry 'Pop' Gehrig
Virginia Gilmore
Myra Tinsley
Bill Dickey
Bill Dickey
Ernie Adams
Miller Huggins
Pierre Watkin
Mr. Twitchell
Harry Harvey
Joe McCarthy
![Bob Meusel]()
Bob Meusel
Robert W. Meusel (as Robert W. Meusel)
![Mark Koenig]()
Mark Koenig
Mark Koenig
![Bill Stern]()
Bill Stern
Bill Stern
Addison Richards
Coach
Hardie Albright
Van Tuyl
Edward Fielding
Clinic Doctor
George Lessey
Mayor of New Rochelle
Edgar Barrier
Hospital Doctor
Douglas Croft
Lou Gehrig as a Boy
![Gene Collins]()
Gene Collins
Billy (Age 8)
David Holt
Billy (Age 17)
Veloz
Specialty Dancer (as Veloz and Yolanda)
![Yolanda]()
Yolanda
Specialty Dancer (as Veloz and Yolanda)
![Ed Agresti]()
Ed Agresti
Barber (uncredited)
![Ernie Alexander]()
Ernie Alexander
Bellhop with Flowers (uncredited)
Hooper Atchley
Lathered Man in Barber Shop (uncredited)
Edwin August
Restaurant Patron (uncredited)
![Bettye Avery]()
Bettye Avery
Nightclub Singer (uncredited)
![Becky Bohanon]()
Becky Bohanon
Little Girl (uncredited)
Lynton Brent
Photographer in Hospital (uncredited)
![Roy Brent]()
Roy Brent
Yankee Ballplayer (uncredited)
Betty Brewer
Little Girl (uncredited)
Don Brodie
Girl Show Barker (uncredited)
Charles Cane
Plumber (uncredited)
![Jack Carr]()
Jack Carr
Plumber (uncredited)
![Burr Caruth]()
Burr Caruth
Village Storekeeper (uncredited)
Eddy Chandler
Motorcycle Cop #2 (uncredited)
Lane Chandler
Mark - Player in Locker Room (uncredited)
![Bill Chaney]()
Bill Chaney
Newsboy (uncredited)
![Jack Chapin]()
Jack Chapin
Photographer (uncredited)
Janet Chapman
Tessie (uncredited)
Spencer Charters
Mr. Larsen (uncredited)
![Porter Chase]()
Porter Chase
Weight Guesser (uncredited)
Dane Clark
Fraternity Boy (uncredited)
Heinie Conklin
Wallpaper Hanger (uncredited)
![Hal Cooke]()
Hal Cooke
Man in Cab (uncredited)
Clancy Cooper
Motorcycle Cop #1 (uncredited)
John Daheim
Reporter in Hospital (uncredited)
![Eva Dennison]()
Eva Dennison
Mrs. Worthington (uncredited)
Lester Dorr
Disappointed Fan #1 (uncredited)
![Peter Du Rey]()
Peter Du Rey
Photographer in Hospital (uncredited)
![Lorna Dunn]()
Lorna Dunn
Clinic Nurse (uncredited)
![Jim Farley]()
Jim Farley
Spectator (uncredited)
Frank Faylen
Yankee Third Base Coach (uncredited)
Walter Fenner
Dentist (uncredited)
Pat Flaherty
Yankee Ballplayer (uncredited)
Rosina Galli
Mrs. Fabrini (uncredited)
Vaughan Glaser
Doctor in Gehrig Home (uncredited)
Mary Gordon
Maid (uncredited)
![Herschel Graham]()
Herschel Graham
Spectator (uncredited)
George Guhl
Second Paper Hanger (uncredited)
Eddie Hall
Reporter in Hospital Room (uncredited)
Harry Hayden
Department Store Manager (uncredited)
Vinton Hayworth
Fraternity Boy (uncredited)
![Oscar 'Dutch' Hendrian]()
Oscar 'Dutch' Hendrian
Furniture Mover (uncredited)
![John Hiestand]()
John Hiestand
Announcer (uncredited)
Earle Hodgins
Bottle Game Operator (uncredited)
Fay Holderness
Spectator (uncredited)
John Ince
Man in Box Seat (uncredited)
Mitchell Ingraham
Barber (uncredited)
![Charles Irwin]()
Charles Irwin
Carnival Batting Game Operator (uncredited)
![Jack Irwin]()
Jack Irwin
Photographer in Hospital (uncredited)
![Sheldon Jett]()
Sheldon Jett
Sportsman at Ballgame (uncredited)
![Payne B. Johnson]()
Payne B. Johnson
Boy in Ball Park (uncredited)
John Kellogg
Fraternity Boy (uncredited)
Colin Kenny
Yankee Player on Train (uncredited)
Donald Kerr
Photographer (uncredited)
![Richard Kipling]()
Richard Kipling
Broker (uncredited)
![Pat Lane]()
Pat Lane
Wheel of Chance Barker (uncredited)
![Larry Lawson]()
Larry Lawson
Barker (uncredited)
Rex Lease
Spectator (uncredited)
Theodore Lorch
Neighbor Leaning Through Window (uncredited)
![Frank Lyman]()
Frank Lyman
Fraternity Boy (uncredited)
Wilbur Mack
Man Outside Yankee Stadium (uncredited)
![Dave Manley]()
Dave Manley
Mayor Fiorello LaGuardia (uncredited)
![Maurice Marks]()
Maurice Marks
Player (uncredited)
![Francisco Marán]()
Francisco Marán
Rathskeller Headwaiter (uncredited)
![John C. McCallum]()
John C. McCallum
Minor Role (uncredited)
![Ralph McCullough]()
Ralph McCullough
Reporter in Hospital (uncredited)
![George McDonald]()
George McDonald
Wally Pipp (uncredited)
Matt McHugh
Strength Machine Operator (uncredited)
![James McNamara]()
James McNamara
Rathskeller Manager (uncredited)
Wilmuth Merkyl
Spectator (uncredited)
Howard M. Mitchell
Sportsman at Ballgame (uncredited)
![Irving Mitchell]()
Irving Mitchell
Headwaiter (uncredited)
![Pat Moriarity]()
Pat Moriarity
Policeman in 1915 (uncredited)
Tom Neal
Fraternity Boy (uncredited)
Ray Noble
Orchestra Leader (uncredited)
Patsy O'Byrne
Scrubwoman (uncredited)
George Offerman, Jr.
Freshman (uncredited)
![John B. Old]()
John B. Old
Reporter (uncredited)
Garry Owen
Scorecard Vendor (uncredited)
Sarah Padden
Mrs. Roberts (uncredited)
Emory Parnell
Chicago Policeman O'Doul (uncredited)
Edward Peil Sr.
Policeman (uncredited)
![Tom Quinn]()
Tom Quinn
Reporter in Hospital (uncredited)
Cyril Ring
Photographer (uncredited)
![Henry Roquemore]()
Henry Roquemore
Disappointed Fan #2 (uncredited)
Art Rowlands
Telephone Man (uncredited)
William Roy
Joe Fabrini (uncredited)
![Rip Russell]()
Rip Russell
Laddie (uncredited)
![Francis Sayles]()
Francis Sayles
Cab Driver (uncredited)
Anita Sharp-Bolster
Sasha's Mother (uncredited)
C. Montague Shaw
Mr. Worthington (uncredited)
![Jack Shea]()
Jack Shea
Hammond (uncredited)
John Sheehan
First Paper Hanger (uncredited)
Jack Stewart
Ed Barrow (uncredited)
![Brick Sullivan]()
Brick Sullivan
Policeman (uncredited)
Ben Taggart
Conductor (uncredited)
Walter Tetley
Cake Delivery Boy (uncredited)
![Jimmy Valentine]()
Jimmy Valentine
Sasha - Boy Playing Baseball (uncredited)
![Gohr Van Vleck]()
Gohr Van Vleck
Furniture Mover (uncredited)
Dorothy Vaughan
Eleanor's Landlady (uncredited)
Dorothy Vernon
Family Friend (uncredited)
Malcolm Waite
Big Strength Machine Contestant (uncredited)
James Westerfield
Spectator (uncredited)
Guy Wilkerson
Sportsman at Ballgame (uncredited)
![Max Willenz]()
Max Willenz
Mr. Colletti (uncredited)
![Buddy Williams]()
Buddy Williams
Bootblack (uncredited)
Charles Williams
Little Strength Machine Contestant (uncredited)
![Robert Winkler]()
Robert Winkler
Murphy (uncredited)
![Allen Wood]()
Allen Wood
Freshman (uncredited)
![Mike Donovan]()
Mike Donovan
![Dick Gordon]()
Dick Gordon
Radio Listener (uncredited)
![Charles Flynn]()
Charles Flynn
Fraternity Boy (uncredited)
![Jack Gardner]()
Jack Gardner
![Anthony Walters]()
Anthony Walters
Merril (uncredited)
